Editorial: 5-HT2A/2B/2C Receptors, Memory, and Neuropsychiatric Disorders

Editorial: 5-HT2A/2B/2C Receptors, Memory, and Neuropsychiatric Disorders

It is very well known that memory formation and forgetting represent important cognitive functions modulated by several neurotransmitters, including serotonin (5-hydroxytryptamine, 5-HT) (e. How does the brain become dysfunctional? Such a question has intrigued neuroscientists for many years. Over recent decades, neuroscience research has shed light on this complex issue and growing evidence is...

Gut Microbiota and Neuropsychiatric Disorders

Brain CB2 Receptors: Implications for Neuropsychiatric Disorders

Although previously thought of as the peripheral cannabinoid receptor, it is now accepted that the CB₂ receptor is expressed in the central nervous system on microglia, astrocytes and subpopulations of neurons. Expression of the CB₂ receptor in the brain is significantly lower than that of the CB₁ receptor. Conflicting findings have been reported on the neurological effects of pharmacological a...

Novel experimental models and paradigms for neuropsychiatric disorders: Editorial.

Neuropsychiatric disorders are increasingly becoming the major health burden in modern society, primarily due to our limited understanding of these diseases, and the lack of sufficient treatments. However, even with the latest technological advances, clinical research still has its limitations (e.g., in terms of controllability of the environment or accessibility of tissue samples). Therefore, ...

Interaction between 5-HT6 receptors and acute stress and corticosterone on fear memory reconsolidation in mice

Introduction: Rrecent studies indicated that serotonergic receptors can be mediate the glucocorticoids’ effects on behavioral procesess. The aim of this study was to determine the role of serotonergic receptor (5-HT6) in the effects of acute stress and corticosterone on fear memory reconsolidation in mice. Materials and Methods: Male adult mice were trained and tested in an inhibitory avoidance...